Rubella IgG kit is designed for qualitative and quantitative detection of class G antibodies for Rubella virus in human serum or plasma by enzyme immunoassay method – ELISA (Sandwich assay).

 

Quantitative detection of specific IgG level in the range from 0 to 240 IU/ml can indicate:

  • current infection;
  • presence of protective immunity as a result of the disease in past (anamnestic antibodies);
  • successfully passed vaccination.

 

K2RG                     Rubella IgG (96 tests)

K2RGB                  Rubella IgG (192 tests)

 

Kit volume, tests (including controls) 96, 192

Analitical sensitivity, IU/ml 0.4

Sensitivity, % 100

Specificity, % 97.2

Range of evaluated concentrations, IU/ml 0-240

Incubation time, minutes 60 + 30

Incubation temperature, °С 37

Sample volume, μl 10

Shelf-life, month 12

 

  • Rubella IgM

Rubella IgM kit is designed for qualitative detection of class M antibodies for Rubella virus in human serum or plasma by enzyme immunoassay method – ELISA (Capture assay).

 

Specific IgM revealing irrespectively their level indicate acute Rubella virus infection.

 

K2RM                    Rubella IgM (96 tests)

Kit volume, tests (including controls) 96

Sensitivity, % 96.4

Specificity, % 100

Incubation time, minutes 60 + 60 + 30

Incubation temperature, °С 37

Sample volume, μl 10

Shelf-life, month 12

 

 

 

 

 

 

 

  • Rubella IgG Avidity

 

Rubella IgG Avidity kit is designed for determination of IgG antibodies avidity for Rubella virus in human serum or plasma by enzyme immunoassay method – ELISA (Sandwich assay).

 

A significant amount of women (about 10-20%), if not subjected to vaccination, will reach fertile age without having acquired immunity against the Rubella virus. The diagnosis of Rubella infection in its acute stage is therefore particularly important in pregnant women. It

is usually performed by testing for the presence of IgM antibodies. Identifying the acute phase of the disease, based upon a single sample however may turn out difficult, either due to IgM persistence (often protracted) or else to the presence of IgM in cases of asymptomatic Rubella infection, which is not threatening for the fetus.

Measuring the avidity of specific IgG was demonstrated to be particularly useful in identifying primary infection. As a matter of fact, the initial IgG antibody response to infection is characterized by antibodies with low avidity, in which binding to the specific antigen sites is easily dissociated.

 

K2RGA                  Rubella IgG Avidity (48 tests)

 

Kit volume, tests (including controls) 48

Sensitivity, % 87.8

Specificity, % 100

Incubation time, minutes 60 + 60 + 30

Incubation temperature, °С 37

Sample volume, μl 10

Shelf-life, month 12