Cytomegalovirus IgG kit is designed for qualitative and quantitative determination of class G antibodies for Cytomegalovirus in human serum or plasma by enzyme immunoassay method – ELISA (Sandwich assay).

 

Specific IgG revealing indicates the latent or chronic form of infection. IgG antibodies are present at:

  • primary infected patients on a late stage of infection development;
  • patients with reactivation of latent infection.

Therefore it is not enough qualitative detection IgG antibodies for CMV for the appropriate diagnostics, especially given high contaminated population.

For differentiation the basic development stages of the CMV-infection it is necessary to detect specific IgG in a quantitative variant

 

K3CG                     Cytomegalovirus IgG (96 tests)

K3CGB                   Cytomegalovirus IgG (192 tests)

 

Kit volume, tests (including controls) 96, 192

Analitical sensitivity, RU/ml 0.07

Sensitivity, % 98.7

Specificity, % 97.5

Range of evaluated concentrations, RU/ml 0-240

Incubation time, minutes 60 + 30

Incubation temperature, °С 37

Sample volume, μl 10

Shelf-life, month 12

 

  • Cytomegalovirus IgM

Cytomegalovirus IgM kit is designed for qualitative detection of class M antibodies for Cytomegalovirus in human serum or plasma by enzyme immunoassay method – ELISA (Capture assay).

 

Specific IgM revealing indicates acute infection or its reactivation.

 

K4CM                    Cytomegalovirus IgM (96 tests)

Kit volume, tests (including controls) 96

Sensitivity, % 93.4

Specificity, % 100

Incubation time, minutes 60 + 60 + 30

Incubation temperature, °С 37

Sample volume, μl 10

Shelf-life, month 12

 

 

  • Cytomegalovirus IgG Avidity

 

Cytomegalovirus IgG Avidity kit is designed for detection of IgG antibodies avidity for Cytomegalovirus in human serum or plasma by enzyme immunoassay method – EIA

(Sandwich assay).

 

Fetal damage is now thought to be mainly due to primary infection, rather than to a re-infection. CMV is also an important cause of complications in organ transplantation, particularly in kidney transplantation. Again in these cases, primary infection is more harmful

than a re-infection.

The diagnosis of recently acquired primary infection by means of specifi c IgM antibodies can be difficult, due to the IgM presence even in recurring infections. In addition, circulating IgM antibodies may persist for a lot of months and even for two years in immunodepressed subjects.

Measuring the avidity of specifi c IgG was demonstrated to be particularly useful in identifying primary infection. As a matter of fact, the initial IgG antibody response to infection is characterized by antibodies with low avidity, in which binding to the specifi c antigen sites is easily dissociated.

 

K3CGA                   Cytomegalovirus IgG Avidity (48 tests)

 

Kit volume, tests (including controls) 48

Sensitivity, % 93.9

Specificity, % 97.4

Incubation time, minutes 60+30+30

Incubation temperature, °С 37

Sample volume, μl 10

Shelf-life, month 12